مشخصات پژوهش

عنوان	Synthesis of bioactive polyaniline-b-polyacrylic acid copolymer nanofibrils as an effective antibacterial and anticancer agent in cancer therapy, especially for HT29 treatment
نوع پژوهش	مقاله چاپ شده
کلیدواژه‌ها	Bioactive polyaniline-b-polyacrylic acid copolymer, nanofibrils, antibacterial and anticancer agent, cancer therapy
چکیده	In this work, a new highly water-soluble copolymer of polyacrylic acid with polyaniline is introduced. Acrylic acid was polymerized via the Reversible Addition Fragmentation Chain Transfer method (RAFT) in the presence of an initiator and the obtained polyacrylic acid was copolymerized with aniline at room temperature. As the main achievements of this work, the resulting block copolymer with nanosized structure revealed favorable solubility in polar solvents, as well as excellent antibacterial and anticancer activities. Therefore, it is an appropriate candidate for medical applications such as wound healing and cancer therapy, especially in HT29 treatment.
پژوهشگران	مجتبی محسنی (نفر پنجم)، حامد تشکریان (نفر چهارم)، سید رضا نبوی (نفر سوم)، مسلم منصور لکورج (نفر دوم)، نازنین باقری (نفر اول)