عنوان
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Synthesis and Antibacterial Evaluation of Novel Spiro[indole-pyrimidine]ones
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نوع پژوهش
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مقاله چاپ شده
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کلیدواژهها
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Novel Spiro[indole-pyrimidine]ones, Synthesis, Antibacterial Evaluation
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چکیده
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An efficient route for the synthesis of novel spiro[indole-pyrimidine]ones in high to excellent yields has been investigated through one-pot reactions of phenacylidenetriphenylphosphoranes, oxindoles, and thiourea. Their antibacterial activities were studied against Gram-positive bacteria and Gram-negative bacteria using disc diffusion method. The results showed that most of the synthesized compounds are effective against Gram-positive bacteria.
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پژوهشگران
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مجتبی محسنی (نفر سوم)، سکینه اصغری قراخیلی (نفر دوم)، مریم پورشب (نفر اول)
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