مشخصات پژوهش

عنوان	Synthesis and antibacterial activity of ethyl 2-amino-6-methyl-5-oxo-4-aryl-5,6-dihydro-4H-pyrano[3,2-c]quinoline-3-carboxylate
نوع پژوهش	مقاله چاپ شده
کلیدواژه‌ها	Three-component reaction, Pyranoquinoline 4-Dimethyl aminopyridine (DMAP), Antibacterial activity
چکیده	The three-component reaction of 4-hydroxy-1-methyl-2(1 H )-quinolinone, aromatic aldehydes and ethyl cyanoacetate was carried out in the presence of a catalytic amount of 4-dimethyl aminopyridine (DMAP) in aqueous ethanol. The reactions result in the formation of pyranoquinoline derivatives in excellent yields. Antibacterial activity has been evaluated against Gram positive and Gram negative bacteria for some of the synthesized compounds. The results indicated that these compounds are moderately effective against bacterial growth and their effectiveness is highest against Pseudomonas aeruginosa.
پژوهشگران	مجتبی محسنی (نفر سوم)، سمانه رمضانی (نفر دوم)، سکینه اصغری قراخیلی (نفر اول)