مشخصات پژوهش

عنوان	Efficient Synthesis of Rhodanine-Based Amides via Passerini Reaction using Tetramethylguanidine-Functionalized Silica Nanoparticles as Reusable Catalyst
نوع پژوهش	مقاله چاپ شده
کلیدواژه‌ها	Passerini reaction, rhodanine-N-acetic acid, tetramethylguanidine, heterogeneous catalysis, antibacterial agents
چکیده	Novel rhodanine-based amide derivatives were prepared in good yields via Passerini reaction of rhodanine-N-acetic acid with aromatic aldehydes and tert-butyl isocyanide in the presence of tetramethylguanidine immobilized on silica nanoparticles (TMG-SiO2 NPs) as a heterogeneous base catalyst. The synthesized compounds were evaluated for their antibacterial effects against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus subtilis.
پژوهشگران	مجتبی محسنی (نفر چهارم)، شیدا برزگر (نفر سوم)، راضیه عظیمی (نفر دوم)، ربابه بهارفر (نفر اول)