عنوان
|
Three-component synthesis of quinolone derivatives bearing 1,3-indandione moiety using pyridinium salts
|
نوع پژوهش
|
مقاله چاپ شده
|
کلیدواژهها
|
Dihydroquinolin-2(1H)-ones 1,3-Indandione Isatin Pyridinium salts
|
چکیده
|
A series of 3,4-disubstituted dihydroquinolin-2(1H)-ones have been synthesized via three-component reaction of 1,3-indandione with isatin derivatives and N-phenacyl pyridinium bromide salts in presence of triethylamine as basic reagent. This procedure affords a highly efficient route for accessing quinolones by ring expansion of isatin via a one-pot pathway. Products were obtained in good to moderate yield without requiring a chromatographic purification step.
|
پژوهشگران
|
نرگس شریعتی (نفر چهارم)، فاطمه تحیتی (نفر سوم)، سکینه اصغری قراخیلی (نفر دوم)، ربابه بهارفر (نفر اول)
|