مشخصات پژوهش

عنوان	MOF-derived Co2CuS4 nanoparticles with gold-decorated reduced graphene oxide for electrochemical determination of chloramphenicol in real samples
نوع پژوهش	مقاله چاپ شده
کلیدواژه‌ها	Sensor, Antibiotic, Dual-core MOF, Transition bi-metallic sulfide, Milk, Honey
چکیده	Despite the beneficial effects of antibiotics such as chloramphenicol (CAP), they exert some destructive impacts on human health. We designed an electrochemical sensor based on reduced graphene oxide (rGO)/Au/Co2CuS4 nanohybrid for determination of CAP in food and biological samples. The Co2CuS4 was synthesized from binuclear metal-organic framework (CoCu-BDC) through a two-step process. Nanohybrid was characterized by X-ray photoelectron spectroscopy and transmission electron microscopy. The rGO/Au/Co2CuS4 provides more active sites and good electrical conductivity to reduce charge transfer resistance and improve the electrocatalytic activity for determination of CAP. The prepared sensor has a wide linear range from 7 to 141 nM with a limit of detection of 2.5 nM and a limit of quantification of 21.92 nM. It also provided high selectivity and repeatability with a relative standard deviation of 2.6%. Stability studies showed that the electrode has acceptable performance with efficiency of 95% after 33 days.
پژوهشگران	سیده فریماه موسوی (نفر چهارم)، سید رضا حسینی زوارمحله (نفر سوم)، شهرام قاسمی میر (نفر دوم)، سید محمدامین داعی ناصری (نفر اول)