مشخصات پژوهش

عنوان	Synthesis of indole based amides using immobilized lipase on graphene oxide (GO@lipase) as a retrievable heterogeneous nano biocatalyst
نوع پژوهش	مقاله چاپ شده
کلیدواژه‌ها	Heterogeneous biocatalysts, Indole-2-carboxylic acid Graphene oxide, Lipase, Multi-component reactions
چکیده	A green and efficient one pot procedure to achieve indole based amides using Passerini reaction involving indole-2-carboxylic acids, aromatic aldehydes and alkyl isocyanides in the presence of immobilized lipase on graphene oxide as a heterogeneous nano biocatalyst has been developed. This method has the advantages of simple operation, mild reaction conditions and good to excellent yields. The features of this method are highlighted by using a retrievable nanostructure catalyst. This process has asserted to be efficient in the synthesis of indole derivatives.
پژوهشگران	ربابه بهارفر (نفر دوم)، سمیه راثی (نفر اول)