مشخصات پژوهش

صفحه نخست /Multicomponent Synthesis of ...
عنوان Multicomponent Synthesis of Novel Class of Isatin and 5-isatinyli-denerhodanine Based Diaminofuran Derivatives
نوع پژوهش مقاله چاپ شده
کلیدواژه‌ها 2, 5-diaminofurans, N-(carboxymethyl)isatin, isocynides, dialkyl acetylenedicarboxylates, rhodanine.
چکیده A simple and efficient method has been developed for the synthesis of a new collection of isatin and 5-isatinylidenerhodanine derivatives carrying furan group, from N-(carboxymethyl)isatin through a multi-component reaction is explained. The reactive 1:1 intermediate formed from the reaction of isocyanides and dialkyl acetylenedicarboxylates was trapped at reflux temperature using N-(carboxymethyl)isatin derivatives to produce poly functionalized furan rings in good yields.
پژوهشگران سمیه راثی (نفر دوم)، ربابه بهارفر (نفر اول)