1403/03/31
سیدمحمدتقی کامل میرمصطفائی

سیدمحمدتقی کامل میرمصطفائی

مرتبه علمی: دانشیار
ارکید: https://orcid.org/0000-0003-2796-4427
تحصیلات: دکترای تخصصی
اسکاپوس:
دانشکده: دانشکده علوم ریاضی
نشانی:
تلفن: 01135302428

مشخصات پژوهش

عنوان
Probability Model of Allele Frequency of Alzheimer’s Disease Genetic Risk Factor
نوع پژوهش
JournalPaper
کلیدواژه‌ها
Allele Frequency, Alzheimer’s Disease, Exponentiated Kumaraswamy Distribution, Single Nucleotide Polymorphisms
سال
2016
مجله iranian journal of health sciences
شناسه DOI
پژوهشگران Afshin Fayyaz Movaghar ، S.M.T.K. MirMostafaee ، Tahura Sadat Borhani

چکیده

Background and Purpose: The identification of genetics risk factors of human diseases is very important. This study is conducted to model the allele frequencies (AFs) of Alzheimer’s disease. Materials and Methods: In this study, several candidate probability distributions are fitted on a data set of Alzheimer’s disease genetic risk factor. Unknown parameters of the considered distributions are estimated, and some criterions of goodness-of-fit are calculated for the sake of comparison. Results: Based on some statistical criterions, the beta distribution gives the best fit on AFs. However, the estimate values of the parameters of beta distribution lead us to the standard uniform distribution. Conclusion: The AFs of Alzheimer’s disease follow the standard uniform distribution.