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Title Chemoselective synthesis of novel aminoindolizines using aminopyridines, acetylenic diesters and a-halo ketones
Type JournalPaper
Keywords Aminopyridines, a-Halo ketones, Acetylenic diesters, Indolizine, Chemoselective synthesis
Abstract A chemoselective synthesis of novel indolizine derivatives were reported via three-component reactions of aminopyridines, acetylenic diesters and a-halo ketones. In these reactions, the zwitterion generated from aminopyridines and acetylenic diesters reacted with a-halo ketones to produce indolizine skeleton in good to high yields under mild reaction conditions.
Researchers Ghasem Firouzzade Pasha (Fifth Researcher), Arastoo Nouri Gorji (Fourth Researcher), Vahideh Behboodi (Third Researcher), Mohammad Qandalee (Second Researcher), Sakineh Asghari (First Researcher)