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Title Microwave-assisted chemoselective copper-catalyzed amination of o-chloro and o-bromobenzoic acids using aromatic amines under solvent free conditions
Type JournalPaper
Keywords Microwave-assisted; Copper-catalyzed; Solvent free; Amination; N-Aryl anthranilic acid
Abstract Copper-catalyzed synthesis of N-aryl anthranilic acid derivatives using effective amination of 2-chloro and 2-bromobenzoic acid under microwave irradiation is reported. Some of the advantages of this method are high chemoselectivity, short reaction times, ease of work up procedure and elimination of the need for acid protection.
Researchers Kamal Alimohammadi (Third Researcher), Manijeh Mohadeszadeh (Second Researcher), Yaghoub Sarrafi (First Researcher)