Title
|
Regioselective synthesis of novel spiroindane-1,3-diones through 1,3-dipolar cycloaddition reactions
|
Type
|
JournalPaper
|
Keywords
|
Spiroindane-1,3-dione, Ninhydrin,Azomethine ylide, 1,3-Dipolar cycloaddition
|
Abstract
|
A facile synthesis of novel spiroindane-1,3-diones has been achieved via 1,3-dipolar cycloaddition of an azomethine ylide, generated in situ from ninhydrin and 1,2,3,4-tetrahydroisoquinoline, with the conjugated double bond of chalcone derivatives. The regiochemistry and structures of the cycloadducts were determined with spectroscopic data and by X-ray crystal structure analysis.
|
Researchers
|
Hamid Reza Khavasi (Fourth Researcher), Kamal Alimohammadi (Third Researcher), Mahshid Hamzehloueian (Second Researcher), Yaghoub Sarrafi (First Researcher)
|