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Title
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An improved catalytic method for the synthesis of 3,3-di(indolyl)oxindoles using Amberlyst 15 as a heterogeneous and reusable catalyst in water
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Type
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JournalPaper
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Keywords
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Indole, Isatin , Amberlyst 15, 3,3-Di(indolyl)oxindoles
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Abstract
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Amberlyst 15 efficiently catalyzed the electrophilic substitution reaction of indoles with isatin derivatives to afford 3,3-di(indolyl)oxindoles in water. An important feature of this protocol is the reaction of 3-methyl-1H-indole with isatins to give the corresponding 3,3-diaryloxindole derivatives in high yields. The catalyst exhibited remarkable reusable activity.
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Researchers
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Nasibeh Norozipoor (Fourth Researcher), Marzieh Sadatshahabi (Third Researcher), Kamal Alimohammadi (Second Researcher), Yaghoub Sarrafi (First Researcher)
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