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Title
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Protective effects of Allium paradoxum against gentamicin-induced nephrotoxicity in mice
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Type
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JournalPaper
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Keywords
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Allium paradoxum,gentamicin , mice
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Abstract
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Allium paradoxum (M.Bieb.) G. Don is a locally known vegetable and is utilized for preparation a variety of local foods in northern of Iran. This study was conducted to quantitatively evaluate the recovery effects of A. paradoxum on gentamicin-induced nephrotoxicity in mice. The curative effect of extracts from the aerial parts and bulbs of A. paradoxum against gentamicin-induced renotoxicity in mice was determined. Both extracts at the dose 200 mg kg offered nephroprotective effect by change in the blood urea nitrogen and creatinine. No statistical difference could be obtained in serum creatinine and blood urea nitrogen of bulb-treated mice compared to normal mice. The result show that bulb extract at 200 mg kg has better activity than aerial parts. 1 1 day day 1 1
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Researchers
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Sakineh Mohammadzadeh (Not In First Six Researchers), Rata Bigdellu (Fifth Researcher), Alireza Naqinezhad (Fourth Researcher), Akbar Hajizadeh Moghaddam (Third Researcher), SEYED MOHAMMAD NABAVI (Second Researcher), SEYED FAZEL NABAVI (First Researcher)
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