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Title
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Cu(II) Schiff Base as Catalyst in the Synthesis of 1,8-Dioxodecahydroacridine
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Type
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JournalPaper
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Keywords
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1,8-Dioxodecahydroacridine, Cu(II) Schiff-base catalyst, multi component reaction, one-pot synthesis, water , solvent.
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Abstract
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The catalytic property of Cu(II) Schiff-base complex in an efficient synthesis of 1,8-dioxodecahydroacridines was investigated. The one-pot three component reaction of dimedone, aromatic aldehydes and aromatic amines or ammonium acetate in water afforded the corresponding 1,8-dioxodecahydroacridines with excellent yields. This reaction was carried out in the presence of 1 mol% of catalysts at room temperature. The reusability of the catalysts was demonstrated by a five-run test without loss of its activity. Also, this catalyst possesses several advantages including mild reaction conditions, lower catalytic loading, shorter reaction times, high yield of the products, inexpensive and cleaner (Green chemistry) reactions.
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Researchers
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Zeinab Roushani (Not In First Six Researchers), Saeed Baghery (Fifth Researcher), Maryam Khaledikia (Fourth Researcher), Hamid Golchoubian (Third Researcher), Hamid R. Mardani (Second Researcher), Seyed Mohammad Vahdat (First Researcher)
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