مشخصات پژوهش

عنوان	Design of turn-on luminescent sensor based on nanostructured molecularly imprinted polymer-coated zirconium metal–organic framework for selective detection of chloramphenicol residues in milk and honey
نوع پژوهش	مقاله چاپ شده
کلیدواژه‌ها	Molecularly imprinted polymer; Turn-on sensor, Fluorescence, Metal-organic framework, Chloramphenicol
چکیده	Herein, an optical sensor based on nanostructured molecularly imprinted polymer (MIP) coated on a luminescent zirconium metal–organic framework (MIP/Zr-LMOF) is introduced, and its performance is investigated for the fluorescent determination of chloramphenicol (CAP) antibiotic residues in milk and honey. To fabricate the sensor, the surface of Zr-LMOF is modified with MIP in the presence of CAP template, resulting in the introduction of recognition sites for antibiotic molecules. The porous structure of Zr-LMOF with specific binding sites for CAP recognition benefiting from coated MIP leads to selective and sensitive detection of antibiotic. The probe yields a linear range for detection of CAP in trace concentrations (0.16–161.56 µg.L−1) and provides a detection limit of 0.013 µg.L−1. Acceptable recoveries are achieved for antibiotic in real samples, which are consistent with that obtained from liquid chromatography–tandem mass spectrometry (LC-MS/MS), confirm the favorable performance of sensor for accurate determination of CAP in practical applications.
پژوهشگران	سید ناصر عزیزی (نفر سوم)، شهرام قاسمی میر (نفر دوم)، فاطمه امیری پور امیری پور (نفر اول)