مشخصات پژوهش

صفحه نخست /A high sensitive ...
عنوان A high sensitive electrochemical nanosensor for simultaneous determination of glutathione, NADH and folic acid
نوع پژوهش مقاله چاپ شده
کلیدواژه‌ها Glutathione; NADH; Folic acid; ZnO/CNTs nanocomposite; Sensor
چکیده In the present study, we report electrosynthesis of 4,5-bis(4-chloroanilino)-1,2-benzendiol (BCB) and its application as a selective electrochemical mediator at a surface of carbon paste electrode (CPE) modified ZnO/CNTs nanocomposite as a simple and rapid voltammetric sensor. The sensor showed an efficient catalytic activity for the electro-oxidation of glutathione (GSH), which leads to a lowered overpotential by more than 203 mV compared to unmodified carbon paste electrode. For the mixture containing GSH, nicotinamide adenine dinucleotide (NADH) and folic acid (FA), the electrooxidation signals were well separated. The square wave voltammetry (SWV) currents increased linearly with their concentration at the ranges of 0.006–161, 1.0–650 and 3.0–700μM, respectively with the detection limits of 0.002, 0.3 and 1.0μM. Finally, the electrode was successfully applied for the voltammetric determination of analytes in real samples with satisfactory results.
پژوهشگران رضا اوجانی (نفر چهارم)، محمد علی خلیل زاده (نفر سوم)، نادر تیموری (نفر دوم)، جهانبخش رئوف (نفر اول)