مشخصات پژوهش

عنوان	Air-assisted liquid–liquid microextraction of Azathioprine based on multivariate optimization and its trace determination in biological samples by high-performance liquid chromatography
نوع پژوهش	مقاله ارائه شده
کلیدواژه‌ها	Azathioprine, Experimental design, Air-assisted liquid–liquid microextraction
چکیده	Azathioprine is an immunosuppressant agent which has been clinically applied in the inhibition of organ rejection for the past thirty [1]. But it has a pancreatitis and hepatic toxicity and suppresses the bone marrow, which makes the patients sensitive to infection. Therefore, determination of Azathioprine concentration in urine and plasma is essential [2]. According to our knowledge, no usage of LLME for the extraction and preconcentration of Azathioprine in plasma and urine samples has been reported thus far. Optimizing the effective factors was done in two stages. First, the effective factors were identified by PBD, then the meaningful factors were optimized by BBD
پژوهشگران	محمد رضا حاج محمدی (نفر دوم)، آرمین فلاح (نفر اول)