مشخصات پژوهش

عنوان	Application of a nanostructured sensor based on graphene and ethyl 2‐(4‐ferrocenyl[1,2,3]triazol‐1‐yl)acetate‐modified carbon paste electrode for determination of methyldopa in the presence of phenylephrine and guaifenesin
نوع پژوهش	مقاله چاپ شده
کلیدواژه‌ها	carbon paste electrode, graphene, guaifenesin, methyldopa, phenylephrine
چکیده	We introduce a new method to determine methyldopa without the interference of phenylephrine and guaifenesin. For this purpose, a carbon paste electrode was modified with graphene and ethyl 2‐(4‐ferrocenyl[1,2,3]triazol‐1‐yl)acetate. According to electrochemical studies, oxidation current of methyldopa on the surface of the modified electrode increased and shifted towards negative potentials. This modified electrode demonstrated two linear ranges of 0.4–30.0 μM and 30.0–500.0 μM with a detection limit of 0.08 μM. No change was observed in the sensitivity of the modified electrode towards methyldopa in the presence of phenylephrine and guaifenesin, which enables the simultaneous or independent measurement of the three moieties. The efficiency of the proposed modified electrode was evaluated through the determination of these substances in real samples.
پژوهشگران	رحمان حسین زاده (نفر پنجم)، پرویز نوروزی (نفر چهارم)، محمد رضا گنجعلی (نفر سوم)، کاوه مولایی (نفر دوم)، هادی بیت اللهی (نفر اول)