عنوان
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Efficient one-pot synthesis of highly functionalized furan fused spirooxindoles using pyridinium salt
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نوع پژوهش
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مقاله ارائه شده
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کلیدواژهها
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multicomponent reaction, spirooxindole, isatin, 3-cyanoacetyl indole, N-phenacyl pyridinium bromide
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چکیده
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A facile and efficient approach for the synthesis of 2-benzoyl-5-(1H-indol-3-yl)-2'-oxo-2H-spiro[furan-3,3'-indoline]-4-carbonitrile derivatives was developed via a one-pot, three-component reaction of isatins with 3-cyanoacetyl indole and N-phenacylpyridinium bromide in the presence of triethylamine. the reaction was carried out in ethanol under reflux conditions, and the products were obtained in good to moderate yields with a simple work-up procedure.
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پژوهشگران
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راضیه عظیمی (نفر سوم)، ربابه بهارفر (نفر دوم)، هاشم باقری (نفر اول)
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