عنوان
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Safe and Efficient Reductive Methylation of Primary and Secondary Amines Using N-Methylpyrrolidine Zinc Borohydride
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نوع پژوهش
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مقاله چاپ شده
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کلیدواژهها
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Amine; formaldehyde; reductive methylation; ZBHNMP
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چکیده
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An efficient, general procedure for reductive methylation of primary and secondary amines with 37% formaldehyde using N-methylpyrrolidine zinc borohydride (ZBHNMP) as a reducing agent gave the corresponding tertiary amines in excellent yields. The reaction was carried out in tetrahydrofuran under neutral conditions at 0–10 C
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پژوهشگران
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کاظم فضلی (نفر چهارم)، فاطمه صالحیان (نفر سوم)، محمود تاجبخش (نفر دوم)، حشمت اله علی نژاد (نفر اول)
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