مشخصات پژوهش

صفحه نخست /Efficient synthesis of ...
عنوان Efficient synthesis of quinazoline derivatives catalyzed by flourinated alcohol
نوع پژوهش مقاله چاپ شده
کلیدواژه‌ها Quinazoline , One-pot synthesis, 1,1,1,3,3,3-Hexafluoroisopropanol
چکیده A facile and efficient protocol is reported for the synthesis of quinazoline derivatives via a one-pot multicomponent reaction of 2-amino-5-chlorobenzophenone, aromatic aldehydes and ammonium acetate using 1,1,1,3,3,3-hexafluoroisopropanol (HFIP). The use of HFIP both as the solvent and catalyst has significant advantages, including avoiding the use of an acidic catalyst and ease of product isolation.
پژوهشگران اکرم وداد مفرد (نفر دوم)، بهروز ملکی (نفر اول)