1403/03/31
محمود تاجبخش

محمود تاجبخش

مرتبه علمی: استاد
ارکید:
تحصیلات: دکترای تخصصی
اسکاپوس:
دانشکده: دانشکده شیمی
نشانی:
تلفن: 09111146981

مشخصات پژوهش

عنوان
A new fluorescent boronic acid sensor based on carbazole for glucose sensing via aggregation induced emission
نوع پژوهش
JournalPaper
کلیدواژه‌ها
Fluorescent sensor, Carbazole, Glucose, Boronic acid
سال
2022
مجله RSC Advances
شناسه DOI
پژوهشگران Mandana Oloub ، Rahman Hosseinzadeh ، mahmood tajbakhsh ، Maryam Mohadjerani

چکیده

A water-soluble fluorescent sensor based on carbazole pyridinium boronic acid (CPBA) was designed and synthesized. Its structure has been confirmed by CHN and 1H and 13C NMR, FT-IR, and MS spectral data. Fluorescence studies of the synthesized chemosensor CPBA showed a selective ratiometric fluorescent response for glucose among different monosaccharides. The results specified that CPBA is a pH sensitive sensor that behaves differently in the absence and presence of glucose in the pH range 4–10. The pH, DLS, Job's plot, UV-visible, and fluorescence titration studies showed that the selectivity of CPBA towards glucose is through the aggregation-induced emission (AIE) phenomenon. The fluorescence emission intensity of CPBA changes by more than 2100 fold by adding glucose, whereas it is 2 fold for fructose. The calculated binding constant value of CPBA for glucose (K ¼ 2.3  106 M1) is 85 times greater than for fructose, indicating the high affinity of the sensor for glucose.