The present study focuses on Fe3O4@Creatine@Cu catalyzed one threecomponent
reaction called “click reaction” to synthesize 1,2,3-triazoles.
Therefore, a mild and green synthesis was developed for 1,3-dipolar cycloaddition
reactions of several various azides and alkynes. This cycloaddition
is a strong synthetic instrument in the creation of a heterocyclic ring, with
wide usages in various fields. Creatine derivative functional groups were
linked to the magnetic nanostructure as an efficient ligand by high
amounts of oxygen and nitrogen to improve the catalyst action.
Afterwards, Cu(II) ions were attached to the surface of the magnetic creatine
structure to gain the last catalyst; then, this catalyst was characterized
using some analysis methods, including scanning electron microscopy
(SEM), Fourier transform infrared spectroscopy (FT-IR), thermogravimetric
analysis (TGA), X-ray diffraction (XRD), and energy-dispersive X-ray analysis
(EDX). The recycled catalyst was performed five times without any considerable
decrease in catalytic magnetic properties and efficiency. Significant
advantages of this procedure include high speed, mild condition, reusability,
high yield, and affordability which make this method attractive.