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Shadmehr Mirdar Harijani

Shadmehr Mirdar Harijani

Academic rank: Professor
Education: PhD.
Faculty: Faculty of Physical Education and Sports Sciences
Address: Professor of Exercise Physiology, Dep. of Exercise physiology, Faculty of sports Sciences, University of Mazandaran P.O.Box 47415-388 Babolsar,Mazandaran Province, IRAN Tel: +98 +111+35302201 & 35302254 Fax: +98+ 111+35302201
Phone: 01135302254


High-intensity interval training-induced inflammation and airway narrowing of the lung parenchyma in male maturing rats
High-intensity interval training . Lung parenchyma ducts . Histometric . Histologic
Journal Comparative Clinical Pathology
Researchers Vahid sobhani ، Shadmehr Mirdar Harijani ، Ehsan Arab zadeh ، Gholamreza Hamidian ، Faezeh Mohammadi


Besides the metabolic beneficial effects of high-intensity interval training (HIIT), it is able to increase the stress on lung parenchyma. This study examined 6 weeks of HIIT-induced inflammation and airway narrowing of the lung parenchyma in male maturing rats. All animals after 2 weeks of familiarization were divided in 3 groups of base (n = 10), HIIT (n = 10), and control (n = 10).HIITwas performed at speed of 20 m/min and ended at speed of 70 m/min (incrementally increase). Twenty-four hours after, the last training session animal was sacrificed and their lung removed. Lung samples were sectioned in 5 μm, stained with H&E, and studied histologically and histometrically. All these variables were measured at the end of exercise intervention. After 6 weeks of HIIT, measures of intima, media, and adventitia anatomical layers of the bronchi and bronchioles of the respiratory tract were significant than the control group (p = 0.05). Mechanical stress caused by excessive ventilation due to HIIT created histological inflammation in the bronchi and bronchioles of the respiratory tract. Thus, HIIT exercise causes reduction in the diameter of the lung parenchyma ducts that can affect the amount of oxygen consumption and consequently affect athletic performance.