We study the dynamics of a generalized inflationary model in which both the scalar field and its derivatives are coupled with the gravity.We consider a general form of the nonminimal derivative coupling in order to have a complete treatment of the model. By expanding the action up to the second order in perturbation, we study the spectrum of the primordial modes of the perturbations. Also, by expanding the action up to the third order and considering the three-point correlation functions, the amplitude of the non-Gaussianity of the primordial perturbations is studied in both equilateral and orthogonal configurations. Finally, by adopting some sort of potentials, we compare the model in hand with the Planck 2015 released observational data and obtain some constraints on the model’s parameters space. As an important result, we show that the nonminimal couplings help to make models of chaotic inflation that would otherwise be in tension with Planck data, in better agreement with the data. This model is consistent with observation at weak coupling limit.