We studied the alpha decay half-life of Americium isotopes (Z ¼ 95) with mass numbers ranging from 223 to 243. Our investigation employed the Coulomb and proximity potential model (CPPM), in addition to alternative analytical and semiempirical formulas. The calculations took into account both experimental and theoretical Q-values, as well as the total alpha kinetic energy. We analyzed the behavior of the hindrance factor concerning changes in the mass numbers of parent nuclei within the range of 223{243, and also examined the impact of magic numbers associated with closed shells. To evaluate the accuracy of our findings, we utilized the SemFIS, UNIV, and Royer formulas to make predictions, which were then compared to the existing experimental data.