Among the common reactions to attain the nuclear fusion, Deuterium and Tritium fusion reaction has attracted the attention of researchers more than other fusion reactions. In fact, the reason for this is the higher cross section of Deuterium and Tritium reaction compared with other fusion reactions. As well as achieving the Deuterium and Tritium fusion reaction at a lower temperature than other fusion reactions is another reason for this content. In this work. We took the hot ion mode into account for nuclear fusion reaction by Deuterium and Tritium fuel; that’s mean unlike the former researches that have been done in this context, we considered different temperatures for ion and electron. Accordingly, we wrote the particle and energy balance equations for Deuterium and Tritium reaction and by numerically solving of these equations studied the plasma parameters and eventually we gained ion to electron temperature ratio.