1403/02/07
میلاد غنی

میلاد غنی

مرتبه علمی: دانشیار
ارکید:
تحصیلات: دکترای تخصصی
اسکاپوس:
دانشکده: دانشکده شیمی
نشانی: مازندران-بابلسر-پردیس دانشگاه مازندران-دانشکده شیمی-گروه شیمی تجزیه
تلفن: 011-35302363

مشخصات پژوهش

عنوان
Cu-Modified Magnetic Creatine as an Efficient Catalyst for Regioselective Preparation of 1,2,3-Triazoles Derivatives
نوع پژوهش
JournalPaper
کلیدواژه‌ها
Creatine; click reaction; triazoles; green chemistry
سال
2022
مجله POLYCYCLIC AROMATIC COMPOUNDS
شناسه DOI
پژوهشگران Farin Laffafchi ، mahmood tajbakhsh ، Yaghoub Sarrafi ، Behrooz Maleki ، Milad Ghani

چکیده

The present study focuses on Fe3O4@Creatine@Cu catalyzed one threecomponent reaction called “click reaction” to synthesize 1,2,3-triazoles. Therefore, a mild and green synthesis was developed for 1,3-dipolar cycloaddition reactions of several various azides and alkynes. This cycloaddition is a strong synthetic instrument in the creation of a heterocyclic ring, with wide usages in various fields. Creatine derivative functional groups were linked to the magnetic nanostructure as an efficient ligand by high amounts of oxygen and nitrogen to improve the catalyst action. Afterwards, Cu(II) ions were attached to the surface of the magnetic creatine structure to gain the last catalyst; then, this catalyst was characterized using some analysis methods, including scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), and energy-dispersive X-ray analysis (EDX). The recycled catalyst was performed five times without any considerable decrease in catalytic magnetic properties and efficiency. Significant advantages of this procedure include high speed, mild condition, reusability, high yield, and affordability which make this method attractive.