2024 : 7 : 22
Khadijeh Nasiri

Khadijeh Nasiri

Academic rank: Assistant Professor
Education: PhD.
Faculty: Faculty of Physical Education and Sports Sciences
Address: University of Mazandaran
Phone: 011-35302217


Zinc Transporters in the Livers of Healthy Male Wistar Rats: An Investigation of the Effects of Aerobic Exercise and Supplementation with Pumpkin Seed and White Pea
ZnT, Aerobic Exercise, Pumpkin Seed, White Pea
Journal Zahedan Journal of Research in Medical Sciences
Researchers Ali Dashti Khavidaki ، Abbass Ghanbabri-Niaki ، Khadijeh Nasiri ، Mohammad Hassan Dashti Khavidaki


Background: The current study aims to investigate the impacts of aerobic exercise with pumpkin seed oil and white pea extract supplementation on the gene expression of the liver zinc transporters of healthy male Wistar rats. Results: Regarding the results of one-way ANOVA, there were no significant changes in serum Zn levels (P = 0.418) as well as gene expression levels of ZnT5 and ZIP14 among intervention groups (P = 0.586 and 0.677, respectively), but ZnT9 gene expression level was significantly changed among the study groups (P = 0.029). Also, the results of the Tukey test showed that six weeks of aerobic exercise along with pumpkin seed oil supplementation had the greatest effect on ZnT5 gene expression. Conclusions: Findings showed that aerobic training along with pumpkin seed oil supplementation had the greatest impact on the up-regulation of ZnT5 as a Zn transporter to retain the blood Zn levels in healthy trained rats, suggesting that pumpkin seed oil can be an effective ergogenic aid for improving circulatory Zn levels.