Drugs have evolved into necessities in modern society. Conversely, it has been shown that people may experience adverse consequences if they are exposed to medications indirectly through water. Advanced treatments like adsorption are necessary in this situation to effectively remove medicinal substances. But newer, innovative nanostructures have been shown to have exceptional adsorptive activity and make good nano adsorbents for drug removal. Graphene oxide nanosheets with varying loading weights (2, 4, and 6%) were used to disperse ZIF 67 nanostructures that were generated in the current work. It was looked into how the Go weight percentage affected the tetracycline's ability to bind to adsorbent. To describe the prepared nanostructure and show that their preparation was successful, a variety of experimental instruments were used. The data was fitted using two isotherm models and two kinetic models. The obtained findings show that the attraction of tetracycline molecules to the GoX/ZIF 67 adsorbent is caused by a range of interactions, such as hydrogen bonding, electrostatic forces, and π π stacking interactions. Tetracycline molecules interact with functional groups on ZIF 67 and graphene oxide when they come into touch with the adsorbent surface. Tetracycline molecules can establish hydrogen bonds with these functional groups, which will aid in the molecules' adsorption. With a 94.27% tetracycline removal rate, Go 4/ZIF 67 has demonstrated the best performance among the synthetic adsorbents