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Abbass Ghanbabri-Niaki

Abbass Ghanbabri-Niaki

Academic rank: Professor
ORCID:
Education: PhD.
ScopusId:
Faculty: Faculty of Physical Education and Sports Sciences
Address:
Phone: 01135302218

Research

Title
Effects of Endurance Training with or without Rosehip Fruits (Rosa canina L) Extraction and D-galactose Solution on Plasmatic Liver Enzymes, Lipid Profiles, Selected Biochemical Variables in Male Rats
Type
JournalPaper
Keywords
Albumin; aminotransferase (AST); bilirubin; cholesterol; creatinine; urea.
Year
2022
Journal BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY
DOI
Researchers Abbass Ghanbabri-Niaki ، Saleh Rahmati-Ahmadabad ، david robert broom ، Ali-Akbar Kolbadinejad1 ، jamal nikbakht ، Martin Hofmeister

Abstract

The aims of the present study were to examine the effects of D-galactose (DG) supplementation on plasma aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), creatinine, albumin, urea, bilirubin, cholesterol, and triglyceride. We also investigated the effects of Rosehip (Rosa canina L) fruit extraction and endurance exercise training on DG-induced changes in the aforementioned variables in male rats. Eighty-six male rats were randomly assigned to 8 groups 1) Control Saline 2) Training Saline 3) Control D-galactose 4) Training D-galactose 5) Control Rosehip 6) Training Rosehip 7) Control combined group and 8) Training combined group. Animals received experiments on the base of groups’ names (eight weeks and five times per week). Seventy-two hours after the last training or control session plasma was collected. The results showed that endurance training significantly increased plasma albumin while reducing ALT and creatinine. Rosehip significantly reduced plasma AST, creatinine, urea, cholesterol, and triglyceride, and increased bilirubin. A combination of training and Rosehip causes an additive effect compared to each intervention alone on AST. The use of DG increased ALT, AST, ALP, creatinine, urea, bilirubin, cholesterol, and triglyceride, while decreasing albumin. The use of Rosehip in combination with DG was able to minimize DG-induced abnormal elevation on some variables. In conclusion, using a high dose of D-galactose solution or high galactose content foods could make a precondition background for the non-alcoholic fatty liver which could be attenuated by crud Rosehip extraction. Thus, it seems that the Rosehip can be considered a hepatoprotective herb.