There is growing concern regarding the potential human health hazard due to exposure to radiofrequency electromagnetic radiation emitted from Wi-Fi equipment. The present experiment was carried out to investigate whether continues exposure of rats to a Wi‐Fi equipment could have harmful effects on brain. For this purpose, oxidative damage on brain tissue were studied in rat model. Twelve male rats were selected for this study and divided into two groups including control and exposed groups, six in each group. After the completion of exposure period, rats were sacrificed and the whole brain tissue was dissected and used for assay of catalase. Catalase activity was determined according to the method of Abei based on the measurement of residual hydrogen peroxide. A significant increase was observed in catalase activity in rats exposed to radiofrequency electromagnetic radiation emitted from Wi-Fi equipment compared with control group (32.07±10.35 Vs 60.91±18.55 U/g tissue, P=0.016). Increased catalase activity may be due to increased hydrogen peroxide production in exposed rat, which is an index of oxidative stress. Oxidative stress, due to sensitivity of neuronal cells, implicated in the development or progression of Alzheimer's disease (AD), Parkinson's disease (PD) and other neurodegenerative diseases. We concluded that continuous exposure to electromagnetic radiation from Wi-Fi equipment may cause oxidative stress, which is implicated in pathologies of the neurodegenerative diseases.
