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Akbar Hajizadeh Moghaddam

Akbar Hajizadeh Moghaddam

Academic rank: Associate Professor
ORCID:
Education: PhD.
ScopusId:
HIndex:
Faculty: Science
Address:
Phone: 01135302453

Research

Title
Protective effects of Allium paradoxum against gentamicin-induced nephrotoxicity in mice
Type
JournalPaper
Keywords
Allium paradoxum,gentamicin , mice
Year
2012
Journal Food & Function
DOI
Researchers SEYED FAZEL NABAVI ، SEYED MOHAMMAD NABAVI ، Akbar Hajizadeh Moghaddam ، Alireza Naqinezhad ، Rata Bigdellu ، Sakineh Mohammadzadeh

Abstract

Allium paradoxum (M.Bieb.) G. Don is a locally known vegetable and is utilized for preparation a variety of local foods in northern of Iran. This study was conducted to quantitatively evaluate the recovery effects of A. paradoxum on gentamicin-induced nephrotoxicity in mice. The curative effect of extracts from the aerial parts and bulbs of A. paradoxum against gentamicin-induced renotoxicity in mice was determined. Both extracts at the dose 200 mg kg offered nephroprotective effect by change in the blood urea nitrogen and creatinine. No statistical difference could be obtained in serum creatinine and blood urea nitrogen of bulb-treated mice compared to normal mice. The result show that bulb extract at 200 mg kg has better activity than aerial parts. 1 1 day day 1 1