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Title Cell Repellent Coatings on Inner Walls of Tubes by Means of Transporting Discharge in Atmospheric Pressure
Type JournalPaper
Keywords Transporting discharge · Cell repellent coating · HDPE tube · Pyrex tube · DEGME monomer · Surface modification
Abstract We report a method to obtain biocompatible PEG copolymer coatings inside high density polyethylene and Pyrex tubes, which was successfully developed by using a transporting discharge. The latter being a dry process, it is easier to apply as compared to the conventional multistep wet chemical techniques. The results presented in this paper show that for a 70 cm tube good cell repellent properties as compared to the control was obtained for the entire length of the tube. The best nonfouling properties with respect to CT-26 (colon cancer) were obtained for coatings presenting the best retention of ether functionalities from the DEGME monomer i.e. between 5 and 25 cm downstream of the tube. These results are interesting for surface modification of biomaterial and biomedical devices, which present hollow bodies.
Researchers Farzaneh Arefi-Khonsari (Fifth Researcher), m Mirshahi (Fourth Researcher), farshad Sohbaztadeh Lonbar (Third Researcher), jerome Pulpytel (Second Researcher), Azadeh Valinataj Omran (First Researcher)