Title
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Solvent-free synthesis of 6-unsubstituted dihydropyrimidinones using 2-pyrrolidonium bisulphate as efficient catalyst
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Type
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JournalPaper
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Keywords
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6-unsubstituted dihydropyrimidinone, 2-pyrrolidonium bisulphate, enaminone, alde-hyde, urea/thiourea
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Abstract
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A one-pot three-component Biginelli-like reaction of enaminones, aldehydes with urea/thiourea in the presence of 2-pyrrolidonium bisulphate as an acidic ionic liquid catalyst for the preparation of 6-unsubstituted dihydropyrimidinones is described. The excellent yield, short reaction time, simple procedure and avoidance of the use of organic solvents are some advantages of this method
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Researchers
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Mahboobeh Mousavi (Fourth Researcher), Mahboobeh Zare (Third Researcher), Heshmatollah Alinezhad (First Researcher), mahmood tajbakhsh (Second Researcher)
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