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Title Solvent-free synthesis of 6-unsubstituted dihydropyrimidinones using 2-pyrrolidonium bisulphate as efficient catalyst
Type JournalPaper
Keywords 6-unsubstituted dihydropyrimidinone, 2-pyrrolidonium bisulphate, enaminone, alde-hyde, urea/thiourea
Abstract A one-pot three-component Biginelli-like reaction of enaminones, aldehydes with urea/thiourea in the presence of 2-pyrrolidonium bisulphate as an acidic ionic liquid catalyst for the preparation of 6-unsubstituted dihydropyrimidinones is described. The excellent yield, short reaction time, simple procedure and avoidance of the use of organic solvents are some advantages of this method
Researchers Mahboobeh Mousavi (Fourth Researcher), Mahboobeh Zare (Third Researcher), Heshmatollah Alinezhad (First Researcher), mahmood tajbakhsh (Second Researcher)