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Title One-Pot Four-Component Synthesis of Thieno[2,3-d]pyrimidin-4-amines via Sequential Gewald/Cyclocondensation Reactions
Type JournalPaper
Keywords One-Pot, Four-Component, Thieno[2,3-d]pyrimidin-4-amines
Abstract Aone-pot four -component synthesis of thieno[2,3-d]pyrimidin-4-amines via sequential Gewald/ cyclocondensation reactionsisdescribed.2-Aminothiophene-3-carbonitriles obtainedfrom the Gewald reaction between cyclicketones,malononitrile ,and sulfurunderwenta condensation ¢cyclization reaction with benzonitriles under solvent-free conditions to afford the title compounds in excellent yields.
Researchers Massoud Amanlou (Not In First Six Researchers), sara saeedi (Fourth Researcher), mehdi soheilzadeh (Third Researcher), Helia Janatian Gazvini (Second Researcher), mehdi adib (First Researcher), mahmood tajbakhsh (Fifth Researcher)