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Title
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Efficient one-pot synthesis of highly functionalized furan fused spirooxindoles using pyridinium salt
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Type
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Presentation
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Keywords
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multicomponent reaction, spirooxindole, isatin, 3-cyanoacetyl indole, N-phenacyl pyridinium bromide
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Abstract
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A facile and efficient approach for the synthesis of 2-benzoyl-5-(1H-indol-3-yl)-2'-oxo-2H-spiro[furan-3,3'-indoline]-4-carbonitrile derivatives was developed via a one-pot, three-component reaction of isatins with 3-cyanoacetyl indole and N-phenacylpyridinium bromide in the presence of triethylamine. the reaction was carried out in ethanol under reflux conditions, and the products were obtained in good to moderate yields with a simple work-up procedure.
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Researchers
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Razieh Azimi (Third Researcher), Robabeh Baharfar (Second Researcher), Hashem Bagheri (First Researcher)
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