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Title Electrochemical sensor for selective determination of N-acetylcysteine in the presence of folic acid using a modified carbon nanotube paste electrode
Type JournalPaper
Keywords N-acetylcysteine Folic acid Electrocatalysis Carbon nanotubes Carbon paste electrode
Abstract In the present paper, a novel benzoylferrocene (BF) modified carbon nanotube paste electrode (BFCNPE) was prepared. The modified electrode was further used for the successful determination of N-acetylcysteine (NAC), and it showed an excellent electrocatalytic oxidation activity toward NAC with a lower overvoltage, pronounced current response, and good sensitivity. Under the optimized experimental conditions, the proposed electrochemical NAC sensor exhibited a linear calibration plot that ranged from 3.0×10−7 to 7.0×10−4 M with a detection limit of 9.0×10−8 M. Also, Square wave voltammetry (SWV) was used for simultaneous determination of NAC and folic acid (FA) at the modified electrode. Finally, the proposed method was applied to the determination of NAC in NAC tablets.
Researchers Rahman Hosseinzadeh (Fourth Researcher), Fatemeh Mirrahimi (Third Researcher), Mohammad Ali Taher (Second Researcher), Hadi Beitollahi (First Researcher)