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Title Efficient Synthesis of Symmetrical Bisamides from Aldehydes and Amides Catalyzed by Silica-Bonded S-Sulfonic Acid Nanoparticles
Type JournalPaper
Keywords Aldehydes; amides; bisamides; silica-bonded S-sulfonic acid nanoparticles; supported catalyst
Abstract Silica-bonded S-sulfonic acid nanoparticles (SBSSANPs) were easily synthesized from silica nanoparticles and showed to be an efficient catalyst in the synthesis the symmetrical N,N0-alkylidene bisamides. Reaction of aldehydes and amides in the presence of the catalyst afforded the corresponding bisamides in good to excellent yields. The extensive range of substrates suggests general applicability of the method. Reusability of the catalyst, simple workup procedure, and short reaction times are other advantages of this protocol.
Researchers Parizad Rezaei (Fourth Researcher), Heshmatollah Alinezhad (Third Researcher), Rahman Hosseinzadeh (Second Researcher), mahmood tajbakhsh (First Researcher)