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Title One-pot regioselective synthesis of 1,4,5-trisubstituted pyrazoles under solvent-free conditions without catalyst
Type JournalPaper
Keywords Cyclization 1,4,5-Trisubstituted pyrazoles b-Dicarbonyl compounds N,N-Dimethylformamide dimethylacetal Arylhydrazines
Abstract A fast, one pot method with excellent yield has been developed for preparation of 1,4,5-trisubstituted pyrazoles. Treatment of b-dicarbonyl compounds with N,N-dimethylformamide dimethylacetal and hydrazine derivatives afforded immediately the desired pyrazoles under solvent-free conditions in the absence of catalyst
Researchers Mahboobeh Zare (Third Researcher), mahmood tajbakhsh (Second Researcher), Heshmatollah Alinezhad (First Researcher)