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Title
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A green method for the synthesis of bis-indolylmethanes and 3,3′-indolyloxindole derivatives using cellulose sulfuric acid under solvent-free conditions
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Type
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JournalPaper
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Keywords
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Aldehydes; Ketones; Cellulose sulfuric acid; Bis-indolylmethanes; 3,30 -Diindolyloxindole derivatives
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Abstract
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A highly efficient green protocol for the preparation of bis-indolylmethanes, bis-2-methylindolylmethanes, bis-1-methylindolylmethanes and 3,3′-diindolyloxindole derivatives from the reaction of indoles with various aldehydes and ketones in the presence of cellulose sulfuric acid under solvent-free conditions is reported. The significant features of this procedure are high yields of the products, mild reaction, solvent-free condition and non-toxicity of the catalyst.
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Researchers
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Fatemeh Salehian (Third Researcher), Asefeh Hagh Haghighi (Second Researcher), Heshmatollah Alinezhad (First Researcher)
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