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Title
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Coupling of Aldehydes, Amines, and Trimethyl Phosphite Promoted by Amberlyst-15: Highly Efficient Synthesis of a-Aminophosphonates
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Type
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JournalPaper
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Keywords
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amines, phosphonates, Amberlyst-15 catalysis, nucleophilic additions, multicomponent reactions
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Abstract
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A three-component reaction promoted by Amberlyst-15 of an amine, an aldehyde, and trimethyl phosphite (Kabachnik– Fields reaction) in one pot under mild conditions affords the corresponding a-aminophosphonate in high yield after a short reaction time at ambient temperature.
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Researchers
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samad khaksar (Fourth Researcher), Heshmatollah Alinezhad (Third Researcher), akbar heydari (Second Researcher), mahmood tajbakhsh (First Researcher)
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