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Title
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Coupling of aldehydes, amines, and trimethyl phosphite promoted by amberlyst-15 Highly efficient synthesis of alpha-aminophosphonates
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Type
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JournalPaper
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Keywords
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amines - phosphonates - Amberlyst-15 catalysis - nucleophilic additions - multicomponent reactions
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Abstract
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A three-component reaction promoted by Amberlyst-15 of an amine, an aldehyde, and trimethyl phosphite (Kabachnik-Fields reaction) in one pot under mild conditions affords the corresponding α-aminophosphonate in high yield after a short reaction time at ambient temperature.
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Researchers
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samad khaksar (Fourth Researcher), Heshmatollah Alinezhad (Third Researcher), akbar heydari (Second Researcher), mahmood tajbakhsh (First Researcher)
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