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Title
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One-Pot Synthesis of 1,8-Dioxodecahydroacridines and Polyhydroquinoline using 1,3-Di (bromo or chloro)-5,5-Dimethylhydantoin as a Novel and Green Catalyst under Solvent-Free Conditions
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Type
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JournalPaper
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Keywords
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Aldehydes, cyclic 1,3-dicarbonyl compounds, ammonium acetate, ethyl acetoacetate, green catalyst, solvent-free conditions, onepot synthesis
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Abstract
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Solvent-free, one-pot synthesis of polyhdroquinoline and 1,8-dioxodecahydroacridine derivatives have been described via Hantzsch condensation of various aldehydes, ammonium acetate with (i) cyclic 1,3-dicarbonyl compounds and ethyl acetoacetate and (ii) cyclic 1,3-dicarbonyl compounds (2 mmoles) in a very simple, efficient, and environmentally benign method using 1,3-(dibromo or dichloro)- 5,5-dimethylhydantoin as a cheap, non-toxic and neutral catalyst with up to excellent yields.
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Researchers
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Samaneh Sedigh Ashrafi (Fourth Researcher), Mina Kermanian (Third Researcher), Reza Tayebee (Second Researcher), Behrooz Maleki (First Researcher)
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