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Title Solvent-free, one-pot synthesis of 2,4,6-triarylpyridines using trichloroisocyanuric acid or N-bromosuccinimide as a novel and neutral catalyst
Type JournalPaper
Keywords 2,4,6-Triarylpyridines; Aldehydes; Ketones; Ammonium acetate; N-Bromosuccinimide; Trichloroisocyanuric acid; Green chemistry.
Abstract A simple and benign protocol has been explored for the preparation of 2,4,6-triarylpyridines by a one-pot reaction between aryl aldehydes, enolizable ketones and ammonium acetate in the presence of N-bromosuccinimide or trichloroisocyanuric acid as green and neutral catalysts. The reactions proceed smoothly at 130 °C under solvent-free conditions to provide 2,4,6-triarylpyridines in good yields.
Researchers Mina Kermanian (Fourth Researcher), Zeinalabedin Sepehr (Third Researcher), Hafezeh Salehabadi (Second Researcher), Behrooz Maleki (First Researcher)