Mazandaran University | CuI NPs immobilized on a ternary hybrid system of magnetic nanosilica, PAMAM dendrimer and trypsin, as an efficient catalyst for A3‑coupling reaction

Title	CuI NPs immobilized on a ternary hybrid system of magnetic nanosilica, PAMAM dendrimer and trypsin, as an efficient catalyst for A3‑coupling reaction
Type	JournalPaper
Keywords	Trypsin enzyme · PAMAM dendrimer · Nanocatalyst · A3-coupling reaction · CuI NPs
Abstract	Preparation of a nanocatalyst ( Fe3O4@SiO2@DNHCS-Tr@CuI) containing PAMAM dendrimer and trypsin enzyme supported on magnetic nanosilica on which CuI NPs were immobilized was reported in this paper. This nanocatalyst was characterized using FT-IR, FE-SEM, EDX, elemental mapping, XRD, and ICP analyses. The catalytic activity of Fe3O4@ SiO2@DNHCS-Tr@CuI was evaluated by A3- coupling reaction, which indicated a highly efficient activity for the synthesis of propargylamines in green conditions, with high yields, short reaction times and easy separation and recovery of the catalyst for further use
Researchers	Rahman Hosseinzadeh (Third Researcher), sahar peiman (First Researcher), Robabeh Baharfar (Second Researcher)

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