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Title
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Synthesis of novel 1,2,3-triazole derivatives of 2,3-dihydroquinazolin-4(1H)-one
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Type
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JournalPaper
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Keywords
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Quinazolin-4(1H)-one 1, 2, 3-Triazole Click chemistry Isatoic anhydride
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Abstract
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This work reports an efficient route for the synthesis of novel 1,2,3-triazole derivatives of 2,3-dihydroquinazolin- 4(1H)-one starting from isatoic anhydride via a three-step reaction. The resulting 2-amino-N-substituted benzamides from the reaction of isatoic anhydride and benzylamines underwent coupling cyclization reaction with 4-(prop-2-yn-1-yloxy)benzaldehyde, and then click reaction with in situ prepared organic azides afforded the title compounds in good yields.
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Researchers
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Tahmineh Akbarzadeh (Not In First Six Researchers), Abbas Shafiee (Not In First Six Researchers), Alireza Foroumadi (Not In First Six Researchers), Heshmatollah Alinezhad (Not In First Six Researchers), Fatemeh Hasanshahi (Fifth Researcher), Niloufar Foroughi (Fourth Researcher), Maryam Karimi (Third Researcher), Mina Saeedi (Second Researcher), Mohammad Mahdavi (First Researcher)
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