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Title
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Synthesis of Novel Benzo[6,7][1,4]oxazepino[4,5-a]quinazolinone Derivatives via Transition-Metal-Free Intramolecular Hydroamination
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Type
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JournalPaper
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Keywords
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hydroamination, 2-aminobenzamides, terminal alkynes, 7-exo-dig, N-heterocycles
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Abstract
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Novel benzo[6,7][1,4]oxazepino[4,5-a]quinazolinone derivatives were synthesized through an efficient 7-exo-dig hydroamination of 3-substituted-2-[2-(prop-2-yn-1-yloxy)phenyl]- 2,3-dihydroquinazolin-4(1H)-ones in the presence of potassium tert-butoxide (KOt-Bu) in DMF at 130 °C.
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Researchers
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Tahmineh Akbarzadeh (Not In First Six Researchers), Abbas Shafiee (Not In First Six Researchers), Alireza Foroumadi (Not In First Six Researchers), Heshmatollah Alinezhad (Fifth Researcher), Maryam Karimi (Fourth Researcher), Mina Saeedi (Third Researcher), Niloufar Foroughi (Second Researcher), Mohammad Mahdavi (First Researcher)
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