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Title
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Efficient synthesis of novel benzo [f]imidazo[1,2-d] [1,4]oxazepine-5(6H)-one derivatives
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Type
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JournalPaper
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Keywords
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Oxazepine 1,2-Diketones Ammonium acetate 2-Formyl phenoxy acetic acid Cyclization
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Abstract
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A convenient and efficient method is described for the synthesis of novel tricyclic scaffolds incorporating an imidazole ring and medium-sized benzoxazepine ring, via the reaction of 1,2-diketons, 2-formyl phenoxy acetic acids and ammonium acetate in acetic acid under reflux conditions, and then the addition of thionyl chloride to produce lactam in the absence of a catalyst.
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Researchers
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mahmood tajbakhsh (Third Researcher), Heshmatollah Alinezhad (Second Researcher), Hossein Yavari (First Researcher)
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